A Short Note On The And Its Effects On Breast Cancer Tissue

3.1. MiR-206 was prominently downregulated in TNBC tissues and inversely correlated with VEGF Quantitative RT-PCR results show that expression levels of miR-206 are obviously lower in TNBC cell lines than those in non-TNBC cell lines (Fig. 1A). Similarly, TNBC tissues express prominently lower levels of miR-206 compared to non-TNBC tissue samples and normal breast tissues (Fig. 1B). It is worth noting that non-TNBC tissues expressed lower miR-206 compared to normal breast tissues but miR-206 levels in non-TNBC tissues were higher than those in TNBC tissues (Fig. 1B). Furthermore, we analyzed the expression levels of VEGF protein determined by immunohistochemical staining in breast cancer tissue samples. VEGF expression levels were inversely correlated with those of miR-206 in breast cancer tissues (Fig. 1C). These results demonstrate that expression levels of miR-206 are predominantly downregulated in TNBC tissues in comparison to non-TNBC tissues and normal breast tissue samples inv ersely correlated with the levels of VEGF. 3.2. MiR-206 mimics predominantly inhibit the invasion of TNBC cells in vitro To investigate whether miR-206 mimics block the invasion of TNBC cells, miR-206 mimics or control oligonucleotides were transfected into TNBC MDA-MB-231 and non-TNBC MCF-7 cells. The invasive cells from treated groups were determined and compared to their controls by Matrigel invasion assay. Fig 2A shows representatives of invasive cell photographs fromShow MoreRelatedThe Importance Of Staying Healthy And Preventative Measures1551 Words   |  7 Pagescorrelating symptoms. For example, aflatoxins, the most common classification of mycotoxins, are the primary cause of liver and kidney cancer especially in poor countries (Aiko and Mehta 2) (Hope 1). 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Progressive Era and the New Deal - 857 Words

Progressive Era and the New Deal (Question 5) During the Progressive Era, the reformers were stricter and did not provide direct help, while the reformers in the New Deal were a little more direct in helping Americans. The progressive era policies were more concerned with correcting the society. All three presidents during this time period, including Theodore Roosevelt, Howard Taft, and Woodrow Wilson, implemented some progressive reforms. It was the government’s policy to correct social and economic problems as well as to provide assistance for the people. Conversely, during the New Deal, most policies and programs were passed by the federal government. One of the greatest programs was the Temperance Movement, the 18th amendment, which†¦show more content†¦Luckily, one of the New Deal programs, the Fair Labor Standard Act, which set down standards for the basic minimum wage and overtime pay while affecting most private and public employment, protected workers rights for them to not suffer like they had been suffering for the last years. Other programs during the New Deal were the civil Works Administration, which created jobs for the unemployed, and the Public Works Administration, which was created to provide economic stimulus and jobs. A very important program passed during the New Deal was the Tennessee Valley Authority, a program established to develop the economy in the Tennessee Valley region, and it was the largest public provider of electricity in the United States. The programs and policies during the Progressive Era and the New Deal differed mainly in that the Progressive Era was not as direct on providing jobs or financial relief and most of the programs were passed by the states. The New Deal was a more direct provision of jobs and financial relief and most of its programs were passed and aided by the federal government. However, both the Progressive Era and the New Deal reformers were able to help the people and were successful in many of their attempts to help people that had been through the Great Depression and all the bad consequences they hadShow MoreRelatedThe Progressive Era And The New Deal1103 Words   |  5 Pagesargued that the New Deal reforms reflected the reform traditions of the Progressive Era. When examining the New Deal, Progressive influence is evident based first off of the social and political issues addressed by reforms. 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Infant Observation - 721 Words

While having breakfast at a local coffee show, I was presented with the opportunity to casually observe a child somewhere between 5 and 6 months. Bailey is a very happy, active, babbling little girl. She was sitting at a table with her mother, and another woman similar in age to mom. I am not sure if this was a relative or a family friend. Bailey was â€Å"propped up† on the bench next to mom using a pillow (I think they are called â€Å"boppy† pillows) and had two or three brightly colored fabric animal toys. I was sitting three tables away from them, but there were four other people at the tables around the baby and her family. Bailey was actively engaging the attention of those around her with laughs and smiles. Bailey did not seem to be afraid†¦show more content†¦She was also very calm (even when Bailey tried to grasp for things on the table) and easily balanced her social interaction with the other woman at the table with her interaction with Bailey. Bailey was clearly exhibiting many of the skills that our book discusses as part of development. One example was her motor skills. Bailey was discovering the world by reaching for and touching items around her. When given a toy she grasped it, looked at it, and used her mouth to taste and chew. The vocal cues she was giving to her mother as well as to the other adults around her that she was seeking attention where another way she was discovering her place in the world. Bailey was observing adults making noises to each other, as well as towards her. While she does not have the skills to understand what these noises mean, she seemed to understand that there was an interaction between them of which she wanted to be a part. In addition to observing Bailey, by seeing her interaction with her mother even in such a brief time there was some understanding as to how Bailey was becoming a pleasant, happy, social child. Her mother was calm, and even toned. She engaged with her child in a pleasant manner, even when correcting her for reaching for things she could not have on the table. While Bailey was allowed to explore her world, her mother kept her safely situated on the bench with her pillow. I am sure there are moments when both mom and Bailey wereShow MoreRelatedObservation Infant Child Observation1809 Words   |  8 PagesOn October 16, 2017, I observed in the infant room from 8:30 a.m. until 11:00 a.m.. The child I observed was a female and just turned eight months old. Indicators given by the child during the observation, show that the child is progressing at a normal developmental pace and even excelling in other areas. Through observing her, I noticed her motor skills were excelling beyond what was expected. She was pulling herself up and standing. 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Formal Analysis of Edgar Degas Ballet Rehearsal Essay Example For Students

Formal Analysis of Edgar Degas Ballet Rehearsal Essay The configuration of the art work ponders a contrast be,even aground and foreground utilizing dualities such as light and dark, energy and serenity, and clarity to obscurity. Line and space pulls the audiences attention across the entirety of the composition. The impressionistic style successfully captures a moment in time, saturated with chaotic elements caught UN-posed and half seen, as they are in real life. Ballet Rehearsals composition successfully blends line, color, light, shadow, and space in order to build an impressive example of visual art. Arranged in the background of the composition are a group of dancers performing arabesques. The dancers, go through back breaking work-outs at the bar or squat, breathless with fatigue, their features sagging, muscles bulging as their bodies graciously , with legs sprawling wide apart, totally devoid to erotic or any other charm, (Honor et al, 2005). Large windows on the far wall allow light to break through and spill onto the wooden floor and a figure, perhaps a teacher, waits and watches from the back right corner of the field of view. We will write a custom essay on Formal Analysis of Edgar Degas Ballet Rehearsal specifically for you for only $16.38 $13.9/page Order now A dominant spiral staircase tucked in the extreme left of the foreground partially obscures the row of dancers behind it To the right a group of resting dancers sit quiet in heir placid corner of the work. Degas rigorously structures his painting with strong diagonals and symmetries, the chaos of the scene dissolves into a clear and understandable composition which achieves a satisfying harmony. This is no surprise; Degas spent hours and hours backstage making preparatory sketches that preceded the artist working with oils on canvas. Brochure 201 1) The elements Of the composition are split into three sections, an energetic clustered section filled with movement, a void of activity in the middle and a serene detailed section meant to be contrasted to the first section. One element of Degas painting ties all of the other elements of the work into a complete image is line. Degas uses the floorboards of the studio to create a path for the viewers focus to follow, Thin lines in the floor invite the gaze from the bottom of the spiral staircase through the two groups of dancers to the top right corner of the painting. These lines that draw us further into the scene produce a wonderful sense to depth. Strong lines tossed at the base of the back wall and between the tan and red portions of the same wall once again pulls the attention t the piece this time to the top to the spiral staircase. The vertical and downward spirals of the staircase bring focus once again to the base of the stairs, Degas successfully utilizes line to connect all of the separate elements contained in the painting, In addition to its unifying quality in the work line also is used to portray the energy in the dancers movements. Y having the dancers in the background extend one arm towards the right and one leg to the left Degas implies line in the forms of their bodies. The extended arms seem to curve and wing downward while the dancers legs swing up, this causes their forms to appear to spiral and twirl just like the staircase. Movement is at the soul off this piece, the Whole composition seems to curve and twirl. Energy build s on the stairs, thrusts foamed through the ballerinas twirling dance and swinging around to the bottom Of the piece where the focus slows before beginning again at the base of the staircase. Degas pallet for the Ballet Rehearsal includes reds, blues, and yellows but relies heavily on browns, tans, gold, and white for the majority of forms in the composition. The floor, staircase and most of the walls are made up of different variants of brown with lighter tints where there is light and darker shades in the shadows. The dancers in the background adorn white almost smoke like tutus complimented with yellow, pink, red and blue bows. All of the dancers in the background have brunette hair except to the dancer closest to the center of the composition who has orange hair. .u2d86382e7a22fc7112ecc2fd18db2c58 , .u2d86382e7a22fc7112ecc2fd18db2c58 .postImageUrl , .u2d86382e7a22fc7112ecc2fd18db2c58 .centered-text-area { min-height: 80px; position: relative; } .u2d86382e7a22fc7112ecc2fd18db2c58 , .u2d86382e7a22fc7112ecc2fd18db2c58:hover , .u2d86382e7a22fc7112ecc2fd18db2c58:visited , .u2d86382e7a22fc7112ecc2fd18db2c58:active { border:0!important; } .u2d86382e7a22fc7112ecc2fd18db2c58 .clearfix:after { content: ""; display: table; clear: both; } .u2d86382e7a22fc7112ecc2fd18db2c58 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u2d86382e7a22fc7112ecc2fd18db2c58:active , .u2d86382e7a22fc7112ecc2fd18db2c58:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u2d86382e7a22fc7112ecc2fd18db2c58 .centered-text-area { width: 100%; position: relative ; } .u2d86382e7a22fc7112ecc2fd18db2c58 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u2d86382e7a22fc7112ecc2fd18db2c58 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u2d86382e7a22fc7112ecc2fd18db2c58 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u2d86382e7a22fc7112ecc2fd18db2c58:hover .ctaButton { background-color: #34495E!important; } .u2d86382e7a22fc7112ecc2fd18db2c58 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u2d86382e7a22fc7112ecc2fd18db2c58 .u2d86382e7a22fc7112ecc2fd18db2c58-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u2d86382e7a22fc7112ecc2fd18db2c58:after { content: ""; display: block; clear: both; } READ: A Critical Analysis of A Midsummer Night's Dream William Shakespeare, born in 1594, is one of the greatest writers in literature EssayThe male figure in the back right corner is wearing a vibrant red shirt which catches ones attention. In the foreground like the other dancers the two here wear the Smokey tutus. A rich yellow bow is wrapped around the first dancers waist and peach shoes hang from her neck. An old woman with silver hair wearing an orange dress stands behind the dancer, Overall the painting has a warmth to it, this warmth is broken up by the blue shall over the second dancer in the foregrounds shoulders and the small bits of blue found in the dancers in the b ackground. At the same time the blues connect the two sections Of the painting containing forms that are separated by the diagonals of the floorboards. Ay using this method Degas brings more life to his piece. On the wall in the background a purplish smudge rests above the dancers heads. The smudge could be a water stain on the wall or places where the paint is coming Off Of the wall, but no matter What it is the additional colors add to the energy of the top left corner of the painting Light and shadow are prevalent throughout the composition. Light appears to fill the room through the large windows in the back ground. Dancers closest to the windows cast shadows into the open area of the dance floor. Shadows are what anchor the dancers forms to the world of the painting. The spiral staircase s a prime example of how varying degrees of light to dark can portray depth and form, Coupled with brush stroke direction this use of light makes the stairs feel like they recede into the painting as well as extending our towards the viewer. Another example of how light and shadow produce form is the dancer with the blue shall in the foreground. Her right shoulder goes trot light to shadow rounding the shoulder, Degas also utilizes the extremes of light and shadow to highlight the differences between the two distinct diagonal halves of the painting. In the calmer more placid bottom right half of the painting contains the charity of the shadow in the composition with the largest darkest shadow being the bottom half of the old ladys dress. The top left diagonal half contains all of the large windows letting light into the scene, this separation could be another comment on the division of the energy in the composition. The depiction of space here in Degas painting is crucial to its composition. The scene is viewed from a fly on the wall perspective perhaps that of the artist or of a member of ballet school. Directly in the front of the field of view a large open section Of the painting divides into two separate but related hubs Of information. All the gossamer prettiness and and glitter seen out front vanish backstage. (Honor et al. 2005). Foreshortening in the staircase, the diagonal receding lines on the floor boards, and the size of the forms in the background partially covered by forms in the foreground creates depth in the work as well as creating a realistic sense of space in the world of the painting. Ballet Rehearsals composition successfully blends line, color, light, shadow, and space in order to build an impr essive example of visual art. In this painting Degas gives his audience a chaotic scene in equilibrium.